Differentially expressed genes on the growth of mouse Leydig cells treated with standardised Eurycoma longifolia extract
نویسندگان
چکیده
منابع مشابه
Investigations on the in vitro effects of aqueous Eurycoma longifolia Jack extract on male reproductive functions
s and Presentations: UWC Science Research Open Day (2011): Poster Presentation Erasmus N, Solomon MC, Fortuin KA, Henkel RR: Effect of Eurycoma longifolia Jack (Tongkat Ali) extract on human spermatozoa in vitro, Bellville, South Africa; abstract book p. 33. 40 Physiology Society of Southern Africa (2012): Oral Presentation Erasmus N, Solomon MC, Fortuin KA, Henkel RR: Effect of aqueous ext...
متن کاملIn Vitro Evaluation of the Effects of Eurycoma longifolia Extract on CYP-Mediated Drug Metabolism
Eurycoma longifolia (Simaroubaceae) is a popular folk medicine that has traditionally been used in Southeast Asia as an antimalarial, aphrodisiac, antidiabetic, and antimicrobial and in antipyretic remedies. This study evaluates the effects of Eurycoma longifolia extract on cytochrome P450 (CYP) enzyme-mediated drug metabolism to predict the potential for herb-drug interactions. Methanolic extr...
متن کاملDecreased expression of alpha-2-HS glycoprotein in the sera of rats treated with Eurycoma longifolia extract
Eurycoma longifolia is a Malaysian native herb that has been widely used as an aphrodisiac and a remedy for andropause. Although the physiological effects of the plant extract were predicted as a result of the alterations in protein expression, the key protein(s) involved in these alterations are still unclear. In the present study, we have investigated the effect of standardized E. longifolia ...
متن کاملThe Effect of Eurycoma Longifolia Jack on Spermatogenesis in Estrogen-Treated Rats
INTRODUCTION There is little data concerning the ability of Eurycoma longifolia Jack (EL) to reverse the inhibitory effects of estrogen on testosterone production and spermatogenesis. The aim of the present study was to determine the effect of EL on testicular histology and sperm count in estrogen-treated male rats. METHODS Adult male Sprague-Dawley rats weighing 200-250 g were divided into f...
متن کاملInhibitory Effect of Eurycoma Longifolia Extract and Eurycomanone on Human Cytochrome P450 Isoforms
Objective: The aim of this study was to evaluate the inhibitory effect of E. longifolia extract on five human cytochrome P450 isoforms. Methods: The inhibitory effect of E. longifolia standardized extract (TAF-273) on five human cytochrome P450 isoforms, namely CYP1A2, CYP3A4, CYP2C9, CYP2C19 and CYP2D6, was determined using a luminescence method. The effect of eurycomanone on cytochrome P450 i...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Molecular Medicine Reports
سال: 2020
ISSN: 1791-2997,1791-3004
DOI: 10.3892/mmr.2020.11485